It is reported to be the oldest Presbyterian structure in north Mississippi. Union troops camped on its grounds in the Civil War and author William Faulkner was married there. The sanctuary burned in August 2022. The first fire truck from the Lafayette County Fire Department arrived on the scene and found the rear of the building fully involved. When the firefighters got inside, they discovered the fire had already reached the attic and was rapidly spreading. At that point the firemen had no choice but to pull out. With the integrity of the structure rapidly deteriorating, firefighters switched to a defensive attack to keep it from spreading as much as possible.

The congregation is currently holding services in the Fellowship Hall. Plans are being made for reconstruction of the sanctuary using as much of the original material as insurance and current building codes will allow.